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Cayman Chemical ANTIBODY MALT 1mg

Supplier: Cayman Chemical 265971 MG

An anticancer agent inhibits the growth of Calu-6 NSCLC and A-375 melanoma cell lines (EC50s 10 and 25 M respectively) induces arrests the cell cycle at the G2/M phase and induces apoptosis of Calu-6 cells in a concentration-dependent manner induces non-apoptotic growth arrest in HUVECs and inhibits VEGF- FGF- and EGF-induced endothelial cord formation in vitro (EC50s 47 103 and 34 nM respectively) reduces hemoglobin content and blood vessel density in a Matrigel plug model of neoangiogenesis reduces tumor growth in a dose-dependent manner in a Calu-6 mouse xenograft model
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