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Cayman Chemical ANTIBODY MT-802 50mg
SDP

Supplier:  Cayman Chemical 3658150 MG

Encompass_Preferred

A c-MET inhibitor (IC50s 0 4-2 nM for wild-type and mutant forms) selective for c-MET over a panel of 13 additional kinases (IC50s 22-7800 nM) but does inhibit Ron and FLT1 (IC50s 7 and 10 nM respectively) inhibits autophosphorylation of FGFR2 and PDGFRa in KATO III cells at 2 UM reduces proliferation in a panel of cancer cell lines including cells expressing constitutively active c-MET FGFR2 or PDGFR (IC50s 1 UM for all) reduces tumor growth in a GTL-16 gastric cancer mouse xenograft model (10-200 mg/kg)

Catalog No. 50-291-3284


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