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AOX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, liquid, OriGene
SDP

Catalog No. 501684753
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100 μL
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Catalog No. Quantity
50-168-4753 100 μL
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Catalog No. 50-168-4753 Supplier OriGene Supplier No. TA890040
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Description

Rabbit Polyclonal Antibody

AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal domit neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2.

Specifications

Antigen AOX1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene AOX1
Gene Accession No. O54754, Q06278, Q9Z0U5
Gene Alias AO, AOH1
Gene Symbols Aox1
Host Species Rabbit
Immunogen Recombit protein of human AOX1
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11761, 316, 54349
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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