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APC Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501558938
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50-155-8938 100 μL
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Catalog No. 50-155-8938 Supplier Bethyl Laboratories, Inc Supplier No. A300979A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal domit pre-maligt disease that usually progresses to maligcy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Specifications

Antigen APC
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene APC
Gene Accession No. P25054
Gene Alias Adenomatous Polyposis Coli, APC, DP2, DP2.5, DP3, FAP, FPC, GS
Gene Symbols APC
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 324
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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