Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA583726

Invitrogen™ APC10 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA583726
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA583726 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA583726 Supplier Invitrogen™ Supplier No. PA583726
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: HNLQEIRQLE LVEPSGWIHV PLTDNHKKPT RTFMIQIAVL ANHQNGRDTH MRQIKIYTPV EESSIGKFPR CTTIDFMMYR SI Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC10
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ANAPC10
Gene Accession No. Q9UM13
Gene Alias 1500026N15Rik; A830003M23Rik; ANAPC10; anaphase promoting complex subunit 10; anaphase-promoting complex subunit 10; APC10; cyclosome subunit 10; DKFZp564L0562; DOC1
Gene Symbols ANAPC10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANAPC10. Recombinant protein control fragment (Product #RP-96720).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10393
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.