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Invitrogen™ APC4 Polyclonal Antibody
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Catalog No. PIPA5100861
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PIPA5100861 100 μL
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Catalog No. PIPA5100861 Supplier Invitrogen™ Supplier No. PA5100861
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ANAPC4.

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC4
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ANAPC4
Gene Accession No. Q91W96, Q9UJX5
Gene Alias 2610306D21Rik; ANAPC4; anaphase promoting complex subunit 4; anaphase-promoting complex subunit 4; APC4; cyclosome subunit 4; D5Ertd249e
Gene Symbols ANAPC4
Host Species Rabbit
Immunogen A synthesized peptide derived from human ANAPC4(Accession Q9UJX5), corresponding to amino acid residues L583-R633.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29945, 305420, 52206
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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