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APOBR Monoclonal Antibody (OTI6D3), TrueMAB™, OriGene
SDP

Catalog No. p-200014539
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100 μL
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50-168-1417 100 μL
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Catalog No. 50-168-1417 Supplier OriGene Supplier No. TA807167
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Mouse Monoclonal Antibody

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remt lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Specifications

Antigen APOBR
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI6D3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene APOBR
Gene Accession No. Q0VD83
Gene Alias APOB100R, APOB48R
Gene Symbols APOBR
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 780-1088 of human APOBR produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55911
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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