Apolipoprotein AI Mouse anti-Human, Mouse, Clone: 1C9G5, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 662061IG150UL

Catalog No. 50-173-6639

Description

This antibody was generated against the C-terminal region of human ApoA1.

Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

Specifications

• Antigen: Apolipoprotein AI
• Classification: Monoclonal
• Concentration: 1.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P02647, Q00623
• Gene Symbols: Apoa1
• Immunogen: Apolipoprotein AI Fusion Protein Ag21920
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1C9G5
• Conjugate: Unconjugated
• Gene: APOA1
• Gene Alias: Apo AI, ApoA I, APOA1, apolipoprotein A I, Apolipoprotein A1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11806, 335
• Content And Storage: -20°C
• Form: Liquid