Invitrogen™ APPL1 Monoclonal Antibody (5G11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549222

Catalog No. PIMA549222

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HL-60 whole cell, human THP-1 whole cell, human PC-3 whole cell, human Hela whole cell, rat brain tissue, mouse brain tissue. IHC: human rectal cancer tissue, human breast cancer tissue, human appendicitis tissue. Flow: U-937 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Specifications

• Antigen: APPL1
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q8K3H0, Q9UKG1
• Gene Symbols: APPL1
• Immunogen: E.coli-derived human APPL/APPL1 recombinant protein (Position: K91-R668).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5G11
• Conjugate: Unconjugated
• Gene: APPL1
• Gene Alias: 2900057D21Rik; 7330406P05Rik; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AI585782; AKT2 interactor; APPL; Appl1; AW209077; BB022931; C88264; DCC-interacting protein 13-alpha; DIP13; DIP13 alpha; DIP13A; DIP13alpha; dip13-alpha; Kiaa1428; MODY14; RGD1309388; signaling adaptor protein DIP13alpha
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26060, 290537, 72993
• Content And Storage: -20°C
• Form: Lyophilized