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Invitrogen™ APPL1 Polyclonal Antibody
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Catalog No. PIPA530501
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100 μL
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PIPA530501 100 μL
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Catalog No. PIPA530501 Supplier Invitrogen™ Supplier No. PA530501
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, MCF-7. Predicted reactivity: Mouse (99%), Zebrafish (86%), Xenopus laevis (89%), Pig (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APPL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene APPL1
Gene Accession No. Q8K3H0, Q9UKG1
Gene Alias 2900057D21Rik; 7330406P05Rik; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AI585782; AKT2 interactor; APPL; Appl1; AW209077; BB022931; C88264; DCC-interacting protein 13-alpha; DIP13; DIP13 alpha; DIP13A; DIP13alpha; dip13-alpha; Kiaa1428; MODY14; RGD1309388; signaling adaptor protein DIP13alpha
Gene Symbols APPL1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human APPL1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26060, 72993
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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