Invitrogen™ APPL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114869

Catalog No. PIPA5114869

Description

Antibody detects endogenous levels of total APPL1.

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Specifications

• Antigen: APPL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APPL1
• Gene Alias: 2900057D21Rik; 7330406P05Rik; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AI585782; AKT2 interactor; APPL; Appl1; AW209077; BB022931; C88264; DCC-interacting protein 13-alpha; DIP13; DIP13 alpha; DIP13A; DIP13alpha; dip13-alpha; Kiaa1428; MODY14; RGD1309388; signaling adaptor protein DIP13alpha
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26060, 72993
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8K3H0, Q9UKG1
• Gene Symbols: APPL1
• Immunogen: A synthesized peptide derived from human APPL1(Accession Q9UKG1), corresponding to amino acid residues L127-T177.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov