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Invitrogen™ Aquaporin 4 Polyclonal Antibody
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Catalog No. PIPA585767
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100 μL
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Catalog No. Quantity
PIPA585767 100 μL
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Catalog No. PIPA585767 Supplier Invitrogen™ Supplier No. PA585767
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Human (92%), Mouse (100%), Rat (98%), Pig (92%), Sheep (95%), Rhesus Monkey (95%), Bovine (95%). Positive Control: mouse brain, rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aquaporin 4
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Free Floating), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene AQP4
Gene Accession No. P47863, P55088
Gene Alias Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols AQP4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Intracellular domain of mouse Aquaporin 4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11829, 25293
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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