Invitrogen™ Aquaporin 5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536529

Catalog No. PIPA536529

Description

This antibody detects endogenous protein at a molecular weight of 36 kDa. Purity is >95% by SDS-PAGE.

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

Specifications

• Antigen: Aquaporin 5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AQP5
• Gene Alias: AQP 5; Aqp5; AQP-5; aquaporin 5; Aquaporin5; aquaporin-5; PPKB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11830, 25241, 362
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P47864, P55064, Q9WTY4
• Gene Symbols: AQP5
• Immunogen: Synthetic peptide corresponding to amino acids 220-265 of Human AQP5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG