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Tocris Bioscience™ AR-C 141990 hydrochloride
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Catalog No. 56581 Shop All Novus Biologicals Products
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56-581 1 mg
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Catalog No. 56-581 Supplier Tocris Bioscience™ Supplier No. 5658/1
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Description

MCT1 inhibitor

AR-C 141990 hydrochloride is a monocarboxylate transporter (MCT1) inhibitor (pKi = 7.6. Exhibits approximately 10-fold selectivity for MCT1 over MCT2 and no significant activity against MCT3 or 4. Inhibits graft versus host response and prolongs cardiac graft survival in a rat model. Immunosuppressant. Also inhibits brain penetration of GHB analog HOCPCA.

Specifications

Chemical Name or Material 5-[[(3R)-3-Hydroxy-1-pyrrolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-6-(4-quinolinylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 2250019-94-2
Assay Percent Range >98%
Quantity 1 mg
Molecular Formula C26H28N4O4S.HCl
Formula Weight Observed MW: 529.05
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