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Invitrogen™ Ara H1 Recombinant Mouse Monoclonal Antibody (10C4)

Catalog No. MA566231
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MA566231 200 μg
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Catalog No. MA566231 Supplier Invitrogen™ Supplier No. MA566231
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Description

Mouse Recombinant Monoclonal Antibody

Ara H1 Recombinant Monoclonal Antibody for ELISA

Ara h 1 is a major allergen found in peanuts (Arachis hypogaea) and is classified as a seed storage protein. It belongs to the vicilin family of 7S globulins and is known for its strong allergenic potential, contributing significantly to peanut allergy, which is among the most common food allergies. Structurally, Ara h 1 is a glycoprotein with a molecular weight of approximately 63.5 kDa, consisting of a trimeric formation that enhances its stability and resistance to digestion. This resistance contributes to its allergenicity, as it can persist in the gastrointestinal tract and elicit immune responses. Immunologically, Ara h 1 contains multiple epitopes recognized by IgE antibodies in susceptible individuals, triggering allergic reactions. Due to its stability and prevalence, Ara h 1 is a key target in diagnostic tests and immunotherapies aimed at desensitizing allergic patients to peanuts. Ongoing research includes characterizing its structure, identifying IgE-binding sites, and understanding its role in mediating allergic responses to develop effective treatments and potentially hypoallergenic peanut varieties.
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Specifications

Antigen Ara H1
Applications ELISA
Classification Recombinant Monoclonal
Clone 10C4
Concentration 5.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Host Species Mouse
Immunogen Peanut allergen Ara H1.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Plant
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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