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ARAP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550604

Catalog No. PA550604


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Description

Description

The antibody detects endogenous levels of total ARAP1 protein.

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
Specifications

Specifications

ARAP1
Polyclonal
Unconjugated
ARAP1
Liquid
ARAP1
Synthetic peptide corresponding to a region derived from internal residues of human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
2.8 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q96P48
CENTD2, KIAA0782
Rabbit
IgG
100 μL
-20°C
Primary
116985
Documents
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