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Invitrogen™ ARHGAP18 Polyclonal Antibody
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Catalog No. PIPA520893
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100 μg
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Catalog No. Quantity
PIPA520893 100 μg
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Catalog No. PIPA520893 Supplier Invitrogen™ Supplier No. PA520893
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Description

Rabbit Polyclonal Antibody

A suggested positive control is NIH-3T3 cell lysate. PA5-20893 can be used with blocking peptide PEP-1007.

ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGAP18
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ARHGAP18
Gene Accession No. Q8K0Q5, Q8N392
Gene Alias 4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; MacGAP; Rho GTPase activating protein 18; rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX
Gene Symbols ARHGAP18
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 293947, 73910, 93663
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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