Invitrogen™ ARHGAP18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520893

Catalog No. PIPA520893

Description

A suggested positive control is NIH-3T3 cell lysate. PA5-20893 can be used with blocking peptide PEP-1007.

ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.

Specifications

• Antigen: ARHGAP18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGAP18
• Gene Alias: 4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; MacGAP; Rho GTPase activating protein 18; rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293947, 73910, 93663
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8K0Q5, Q8N392
• Gene Symbols: ARHGAP18
• Immunogen: A 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov