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  6. ARHGAP24 Rabbit anti-Canine, Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech 

ARHGAP24 Rabbit anti-Canine, Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
SDP

Catalog No. p-7209002 Shop All Proteintech Group Inc Products
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50-173-2250 150 μL
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Catalog No. 50-173-2250 Supplier Proteintech Group Inc Supplier No. 188341AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody may recognize all the isoforms of ARHGAP24 except isoform 5.

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

Specifications

Antigen ARHGAP24
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ARHGAP24
Gene Accession No. Q5U2Z7, Q8C4V1, Q8N264
Gene Alias ARHGAP24, Filamin A associated RhoGAP, FILGAP, p73, p73RhoGAP, RC GAP72, RCGAP72, Rho type GTPase activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY SAR 88
Gene Symbols ARHGAP24
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100005116, 231532, 305156, 478463, 83478
Target Species Canine, Human, Mouse, Rat, Zebrafish
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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