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ARHGEF10 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501564806
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50-156-4806 100 μL
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Catalog No. 50-156-4806 Supplier Bethyl Laboratories, Inc Supplier No. A303309A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems. Defects in the gene encoding ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV), an autosomal domit disorders that is characterized by a reduction in nerve velocities resulting from lack of proper myelination.

Specifications

Antigen ARHGEF10
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ARHGEF10
Gene Accession No. O15013
Gene Alias Rho guanine nucleotide exchange factor 10, ARHGEF10, KIAA0294
Gene Symbols ARHGEF10
Host Species Rabbit
Immunogen Between 950 and 1000
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9639
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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