ARHGEF10 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303309A

Catalog No. 50-156-4806

Description

The recommended shelf life for this product is 1 year from date of receipt.

ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems. Defects in the gene encoding ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV), an autosomal domit disorders that is characterized by a reduction in nerve velocities resulting from lack of proper myelination.

Specifications

• Antigen: ARHGEF10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGEF10
• Gene Alias: Rho guanine nucleotide exchange factor 10, ARHGEF10, KIAA0294
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9639
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: O15013
• Gene Symbols: ARHGEF10
• Immunogen: Between 950 and 1000
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG