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ARMETL1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501734684 Shop All Proteintech Group Inc Products
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50-173-4684 150 μL
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Catalog No. 50-173-4684 Supplier Proteintech Group Inc Supplier No. 250351AP150UL
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Description

Rabbit Polyclonal Antibody

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.

Specifications

Antigen ARMETL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CDNF
Gene Accession No. Q49AH0, Q8CC36
Gene Alias ARMET like protein 1, ARMETL1, cdnf
Gene Symbols CDNF
Host Species Rabbit
Immunogen ARMETL1 Fusion Protein Ag18972
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227526, 441549
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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