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Invitrogen™ ARNT2 Polyclonal Antibody
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Catalog No. PIPA530338
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100 μL
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PIPA530338 100 μL
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Catalog No. PIPA530338 Supplier Invitrogen™ Supplier No. PA530338
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Mouse brain. Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (88%), Xenopus laevis (91%), Sheep (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

AhR, ARNT1, ARNT2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common 'PAS' motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator proteins (Arnt 1 or Arnt 2) are required for ligand-dependent nuclear translocation of the Ah receptor and are also necessary for Ah receptor binding to the XRE element. BMAL1 (Brain and Muscle Arnt-like protein 1), also designated Arnt 3, TIC, JAP3 or MOP-3, has been shown to dimerize with Clock and bind to the promoter region of mPer1, suggesting that this protein plays a role in regulation of circadian oscillation in mammals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARNT2
Applications Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Arnt2
Gene Accession No. Q61324, Q9HBZ2
Gene Alias Ah receptor nuclear translocator; Arnt; ARNT 2; ARNT protein 2; Arnt2; arnt2a; ARNT2b; ARNT2c; arnt2X; Aryl hydrocarbon receptor nuclear translocator 2; aryl hydrocarbon receptor nuclear translocator 2A; aryl hydrocarbon receptor nuclear translocator type 2a; aryl hydrocarbon receptor nuclear translocator type 2b; aryl hydrocarbon receptor nuclear translocator type 2c; aryl-hydrocarbon receptor nuclear translocator 2; bHLHe1; bHLH-PAS factor ARNT2B; chunp6921; Class E basic helix-loop-helix protein 1; Hif-2b; KIAA0307; mKIAA0307; unm t30256; unm_t30256; WEDAS; zfARNT2; zfARNT2a; zfARNT2b; zfARNT2c
Gene Symbols Arnt2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ARNT2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11864, 9915
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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