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Invitrogen™ Aromatase Polyclonal Antibody
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Catalog No. APPA6532
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100 μL
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APPA6532 100 μL
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Catalog No. APPA6532 Supplier Invitrogen™ Supplier No. PA116532
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Description

Rabbit Polyclonal Antibody

This antibody is expected to react with equine (91%), bovine and rabbit (90%), porcine (83%), ovine, goat and canine (81%) based on sequence homology. Suggested positive control: antigen standard for CYP19A1 (transient overexpression lysate), human Fetal Temporal Lobe protein.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aromatase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Cyp19a1
Gene Accession No. P11511, P22443, P28649, Q29605
Gene Alias Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase
Gene Symbols Cyp19a1
Host Species Rabbit
Immunogen A synthetic peptide made to a C-terminal portion of the human Aromatase protein (between residues 400-502).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100328545, 13075, 1588, 25147
Target Species Human, Mouse, Rat, Rabbit, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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