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Aromatase Polyclonal Antibody, Invitrogen™

Catalog No. 01950118 Shop All Thermo Scientific Products
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Catalog No. Quantity
01-950-118 50 μg
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Catalog No. 01-950-118 Supplier Thermo Scientific Supplier No. PA121398

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Description

Rabbit Polyclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aromatase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 30% glycerol, 5mM EDTA and 0.03% ProClin 300; pH 7.2
Gene Cyp19a1
Gene Accession No. O46512, P11511, P19098, P22443, P28649, P46194, Q29605, Q29624
Gene Alias Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase
Gene Symbols Cyp19a1
Host Species Rabbit
Immunogen Synthetic peptide surrounding amino acid 385 of human Aromatase
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009712, 100328545, 13075, 1588, 25147, 281740, 403331, 414854
Target Species Bovine, Chicken, Equine, Human, Mouse, Pig, Rabbit, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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