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Invitrogen™ ARTS Polyclonal Antibody
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Catalog No. PIPA124694
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PIPA124694 50 μL
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Catalog No. PIPA124694 Supplier Invitrogen™ Supplier No. PA124694
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Description

Rabbit Polyclonal Antibody

PA1-24694 is expected to cross react with mouse (100% conserved) due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARTS
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene SEPTIN4
Gene Accession No. O43236
Gene Alias 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bh5; BRADEION; Bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; EG3-1RVC; EG3RVC; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; H5; hCDCREL-2; hucep-7; MART; M-Septin; OTTMUSG00000001265; peanut-like 2; peanut-like 2 homolog; peanut-like protein 2; PNUTL2; SEP4; Sept4; septin 4; septin H5; Septin4; septin-4; septin-M; Uncharacterized protein C17orf47
Gene Symbols SEPTIN4
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the C-terminal region of human ARTS (amino acids 247-266 with N-terminal added lysine) conjugated to KLH.
Purification Method IgG fraction
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5414
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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