Invitrogen™ Arylsulfatase G Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554729

Catalog No. PIPA554729

Description

Immunogen sequence: YVTGIIGKWH LGHHGSYHPN FRGFDYYFGI PYSHDMGCTD TPGYNHPPCP ACPQGDGPSR NLQRDCYTDV ALPLYENLNI VEQPV Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

Specifications

• Antigen: Arylsulfatase G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARSG
• Gene Alias: 6330406P08Rik; AI846872; Arsg; Arylsulfatase G; ASG; KIAA1001; RGD1306571; UNQ839/PRO1777
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22901
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96EG1
• Gene Symbols: ARSG
• Immunogen: Recombinant protein corresponding to Human Arylsulfatase G. Recombinant protein control fragment (Product #RP-93287).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG