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Abcam AS601245 JNK Inhibitor, Selective, ATP Competitive, Solid, 25 mg

Catalog No. 502705410
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50-270-5410 25 mg
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Catalog No. 50-270-5410 Supplier Abcam Supplier No. AB14519425MG
May include imposed supplier surcharges.
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Description

Potent and selective ATP-competitive JNK inhibitor that is blood-brain barrier and cell-permeable.

  • Potent and selective: ATP-competitive JNK inhibitor.
  • Activity: IC50 values are 150 nM, 220 nM, and 70 nM for hJNK1, hJNK2, and hJNK3 respectively.
  • Biological effects: Reduces cell adhesion and migration in cancer cells; exhibits neuroprotective and anti-ischemic effects in vivo.
  • Properties: Blood-brain barrier permeable and cell-permeable.
  • Purity: >95%.
  • Molecular weight: 372.4 Da.
  • Form: Solid.

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule JNK (hJNK1, hJNK2, hJNK3)
Shipping Condition Ambient
Form Solid
Alternate Part Number AS601245
Buffer 100% 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
Content And Storage Store at -20°C.
Formulation 100% 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
Quantity 25 mg
For Use With (Application) Cancer research, Neuroprotection, Anti-ischemic studies
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