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Abcam AS601245 JNK Inhibitor, Selective, ATP Competitive, Solid, 5 mg

Catalog No. 502705409
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50-270-5409 5 mg
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Catalog No. 50-270-5409 Supplier Abcam Supplier No. AB1451945MG
May include imposed supplier surcharges.
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Description

Potent, selective, and cell-permeable ATP-competitive JNK inhibitor that reduces cancer cell adhesion and migration.

  • Potency: Potent, selective, ATP competitive JNK inhibitor (IC50 values are 150, 220 and 70 nM for hJNK1, 2 and 3 respectively)
  • Physical Properties: MW 372.4 Da, Purity >95%, Solid form
  • Biological Activity: Reduces cell adhesion and migration in cancer cells; shows neuroprotective and anti-ischemic effects in vivo
  • Characteristics: Blood-brain barrier and cell-permeable
  • Composition: 100% 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule JNK (hJNK1, hJNK2, hJNK3)
Shipping Condition Ambient
Buffer 100% 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
Content And Storage Store at -20°C.
Form Solid
Substrate Properties Chemical Substrate
Formulation 100% 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
Quantity 5 mg
For Use With (Application) Cancer research, Neuroprotection, Anti-ischemic studies
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