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Invitrogen™ ASGR1 Monoclonal Antibody (8D7), FITC
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Catalog No. FERMA548985
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100 μg
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Catalog No. Quantity
FERMA548985 100 μg
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Catalog No. FERMA548985 Supplier Invitrogen™ Supplier No. MA548985
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Description

Mouse Monoclonal Antibody

The monoclonal antibody 8D7 is cross reactive with human ASGPR.

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASGR1
Applications Flow Cytometry, Inhibition Assays, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 8D7
Concentration 100 μg/mL
Conjugate FITC
Formulation PBS with 1% BSA and 0.02% sodium azide
Gene Asgr1
Gene Accession No. P02706
Gene Alias ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)
Gene Symbols Asgr1
Host Species Mouse
Immunogen Crude rat liver membrane extracts.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24210
Target Species Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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