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ASGR1 Mouse anti-Human, Mouse, Porcine, Clone: 1G5F5, Proteintech
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Catalog No. p-7213100 Shop All Proteintech Group Inc Products
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50-173-7109 150 μL
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Catalog No. 50-173-7109 Supplier Proteintech Group Inc Supplier No. 666921IG150UL
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Mouse Monoclonal Antibody

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalisation and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i.e. it is present on the sinusoidal and lateral palasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.

Specifications

Antigen ASGR1
Applications Western Blot
Classification Monoclonal
Clone 1G5F5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ASGR1
Gene Accession No. P07306, P34927
Gene Alias ASGP R 1, ASGPR, ASGPR 1, ASGR1, asialoglycoprotein receptor 1, CLEC4H1, Hepatic lectin H1, HL 1, Hs.12056
Gene Symbols ASGR1
Host Species Mouse
Immunogen ASGR1 Fusion Protein Ag2310
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100625649, 11889, 432
Target Species Human, Mouse, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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