ASH2L Monoclonal Antibody (OTI1A4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810987

Catalog No. 50-168-3751

Description

Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.

Specifications

• Antigen: ASH2L
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9UBL3
• Gene Symbols: ASH2L
• Immunogen: Human recombit protein fragment corresponding to amino acids 347-628 of human ASH2L produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1A4
• Conjugate: Unconjugated
• Gene: ASH2L
• Gene Alias: ASH2, ASH2L1, ASH2L2, Bre2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9070
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid