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Tocris Bioscience™ ASP 3026

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

$267.96 - $1115.92

Specifications

Chemical Name or Material N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
CAS 1097917-15-1
Target ALK Inhibitors
Molecular Formula C29H40N8O3S
Formula Weight 580.74
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
53-101-0
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Tocris Bioscience™
5310/10
10 mg
Each for $267.96
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53-105-0
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Tocris Bioscience™
5310/50
50 mg
Each for $1,115.92
Add to Cart
 
Description

Description

Potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 3.5 nM). Also inhibits Ack and ROS1 activity (IC50 values are 5.8 and 8.9 nM respectively). Attenuates proliferation, and induces apoptosis of NPM-ALK+ T cell anaplastic large-cell lymphoma (ALCL) cells in vitro. Suppresses tumor growth of NPM-ALK+ ALCL cell xenografts in mice. Causes tumor shrinkage in hEML4-ALK transgenic mice. Orally available.
Specifications

Specifications

N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
ALK Inhibitors
580.74
1097917-15-1
C29H40N8O3S
>99%
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
Documents

Documents

Product Certifications
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