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ASPP2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501558530
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50-155-8530 20 μL
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Catalog No. 50-155-8530 Supplier Bethyl Laboratories, Inc Supplier No. A300819AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specifications

Antigen ASPP2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene TP53BP2
Gene Accession No. Q13625
Gene Alias 53BP2, ASPP2, BBP, P53BP2, PPP1R13A, BCL2-binding protein; apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2
Gene Symbols TP53BP2
Host Species Rabbit
Immunogen Between 425 and 475
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7159
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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