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Invitrogen™ Ataxin 7 Monoclonal Antibody (3SCA-1C1)
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Catalog No. PIMA3083
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50 μL
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PIMA3083 50 μL
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Catalog No. PIMA3083 Supplier Invitrogen™ Supplier No. MA3083
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Description

Mouse Monoclonal Antibody

MA3-083 detects Ataxin 7 from human and mouse samples. MA3-083 has been successfully used in Western blot, immunofluorescence, and ELISA applications. The MA3-083 epitope is mapped between aa 66 and aa 119.

Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ataxin 7
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3SCA-1C1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene ATXN7
Gene Accession No. O15265, Q8R4I1
Gene Alias A430107N12Rik; ADCAII; AI627028; Ataxin 7; Ataxin7; Ataxin-7; ATXN7; Atxn7-PA; Atxn7-PB; Atxn7-PC; Atxn7-PD; CG9866; CG9866-PA; CG9866-PB; CG9866-PC; CG9866-PD; Dmel\CG9866; Dmel_CG9866; LD40170p; OPCA3; RGD1562692; SCA7; spinocerebellar ataxia 7 homolog; spinocerebellar ataxia type 7 protein; Spinocerebellar ataxia type 7 protein homolog
Gene Symbols ATXN7
Host Species Mouse
Immunogen Recombinant human Ataxin 7 aa 1 - 229.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246103, 6314
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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