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ATF2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501560907
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Catalog No. Quantity
50-156-0907 20 μL
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Catalog No. 50-156-0907 Supplier Bethyl Laboratories, Inc Supplier No. A301650AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.

Specifications

Antigen ATF2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ATF2
Gene Accession No. P15336
Gene Alias Activating Transcription Factor, CRE-BP1
Gene Symbols ATF2
Host Species Rabbit
Immunogen Between 437 and 487
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1386
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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