Invitrogen™ ATF2 Recombinant Rabbit Monoclonal Antibody (3D12)

Catalog No.	Quantity
PIMA533115	100 μL

Catalog No. PIMA533115

Supplier: Invitrogen™ MA533115

Description

Rabbit Recombinant Monoclonal Antibody

ATF2 Recombinant Monoclonal Antibody for ELISA, ICC/IF, IHC (P), Western Blot

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.

Specifications

• Antigen: ATF2
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 3D12
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Atf2
• Gene Accession No.: P15336, P16951, Q00969
• Gene Alias: Activating 2; Activating transcription factor 2; activating transcription factor 2 splice variant ATF2-var2; ATF2; Atf-2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; CREB2; CREB-2; CRE-BP; CREBP1; CRE-BP1; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; D130078H02Rik; D18875; HB16; Histone acetyltransferase ATF2; MGC111558; mXBP; MXBP protein; OTTHUMP00000205345; OTTHUMP00000205347; OTTHUMP00000205348; OTTHUMP00000205350; OTTHUMP00000205352; OTTHUMP00000205353; OTTHUMP00000205354; Tg(Gzma-Klra1)7Wum; TREB7
• Gene Symbols: Atf2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human ATF2.
• Purification Method: Protein G, Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11909, 1386, 81647
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C or -80°C if preferred
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG