ATF4 Mouse anti-Human, Mouse, Clone: 3E4C5, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 600351IG150UL

Catalog No. 50-173-6199

Description

This antibody is a mouse monoclonal antibody raised against full length human ATF4 antigen. The antibody recognizes the 38 kDa ATF4 protein and its phosphorylated forms (50 kDa).

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Specifications

• Antigen: ATF4
• Classification: Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P18848, Q06507
• Gene Symbols: ATF4
• Immunogen: ATF4 Fusion Protein Ag1279
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 3E4C5
• Conjugate: Unconjugated
• Gene: ATF4
• Gene Alias: ATF4, CREB 2, CREB2, DNA binding protein TAXREB67, TAXREB67, TXREB
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 11911, 468
• Content And Storage: -20°C
• Form: Liquid