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ATF4 Mouse anti-Human, Mouse, Clone: 3E4C5, Proteintech
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Catalog No. 501736199 Shop All Proteintech Group Inc Products
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50-173-6199 150 μL
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Catalog No. 50-173-6199 Supplier Proteintech Group Inc Supplier No. 600351IG150UL
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Description

Mouse Monoclonal Antibody

This antibody is a mouse monoclonal antibody raised against full length human ATF4 antigen. The antibody recognizes the 38 kDa ATF4 protein and its phosphorylated forms (50 kDa).

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Specifications

Antigen ATF4
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3E4C5
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ATF4
Gene Accession No. P18848, Q06507
Gene Alias ATF4, CREB 2, CREB2, DNA binding protein TAXREB67, TAXREB67, TXREB
Gene Symbols ATF4
Host Species Mouse
Immunogen ATF4 Fusion Protein Ag1279
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11911, 468
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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