Invitrogen™ ATG4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596183

Catalog No. PIPA596183

Description

Immunogen sequence: SKGTSAYCSA WKPLLLIVPL RLGINQINPV YVDAFKECFK MPQSLGALGG KPNNAYYFIG FLGDELIFLD PHTTQTFVDT EENGTVNDQT FHCLQSPQRM NILNLDPSVA LGFFCKEEKD FDNWCSLVQK EILKENLRMF ELVQKHPSHW PPFVPPAKPE VTTTGAEFID STEQLEEFDL EEDFEILSV Positive Samples: HepG2, Jurkat, 22Rv1, K-562, BT-474, Mouse skeletal muscle; Cellular Location: Cytoplasm.

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Specifications

• Antigen: ATG4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATG4A
• Gene Alias: AI627006; APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; APG4A; ATG4 autophagy related 4 homolog A; Atg4a; Atg4al; Atg4al1; AUTL2; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; autophagin-2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A cysteine peptidase; autophagy related 4A, cysteine peptidase; autophagy related 4A, cysteine peptidase-like 1; autophagy-related 4A; autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; AV169859; cysteine protease APG4A; cysteine protease ATG4A; hAPG4A; MGC107179
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115201, 666468, 678769
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q8C9S8, Q8WYN0
• Gene Symbols: ATG4A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-398 of human ATG4A (NP_4431682).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG