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ATGL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501736047 Shop All Proteintech Group Inc Products
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50-173-6047 150 μL
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Catalog No. 50-173-6047 Supplier Proteintech Group Inc Supplier No. 551901AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody is specific to ATGL.

Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.

Specifications

Antigen ATGL
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PNPLA2
Gene Accession No. P0C548, Q8BJ56, Q96AD5
Gene Alias 1110001C14Rik, Adipose Triglyceride Lipase, ATGL, DESNUTRIN, FP17548, IPLA2 zeta, PEDF R, PNPLA2, Transport secretion protein 2, TTS 2.2, TTS2, TTS2.2
Gene Symbols Pnpla2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361676, 57104, 66853
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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