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Tocris Bioscience™ ATI 2341
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Catalog No. 57951
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57951 1 mg
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Catalog No. 57951 Supplier Tocris Bioscience™ Supplier No. 5795/1
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Description

CXCR4 allosteric agonist

ATI 2341 is a CXCR4 allosteric agonist (EC50 = 194 nM). Induces chemotaxis in CXCR4-expressing cells in vitro. Mobilizes polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) from bone marrow niche in vivo. Exhibits biased signaling towards Gi proteins over G13 and β-arrestin.

Specifications

Purity 0.95
CAS 1337878-62-2
Content And Storage Store at -20°C
Description Chemokine Receptor Agonists
Molecular Weight (g/mol) Observed M.W.: 2256.82
Quantity 1 mg
Structural Form C104H178N26O25S2
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