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Tocris Bioscience™ Atosiban
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Catalog No. 633210
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent oxytocin receptor antagonist

Atosiban is a potent oxytocin receptor (OTR) antagonist. Inhibits oxytocin-induced increase in Ca2+ concentration in myometrial cells in vitro (IC50 = 5 nM) Activates NF-κB and MAPK pathways in human amnion via Gαi signaling, resulting in pro-inflammatory effects. Inhibits oxytocin-induced uterine contractions in vivo and in vitro. Effective in a rat preterm labor model.

Specifications

CAS 90779-69-4
Content And Storage Store at -20°C
Molecular Weight (g/mol) Observed MW: 994.19
Quantity 10 mg
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