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Invitrogen™ ATP11C Polyclonal Antibody
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Catalog No. PIPA5107072
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PIPA5107072 100 μL
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Catalog No. PIPA5107072 Supplier Invitrogen™ Supplier No. PA5107072
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Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% Immunogen sequence: GLKVWVLTGD KMETAKSTCY ACRLFQTNTE LLELTTKTIE ESERKEDRLH.

The ATP11C gene encodes a protein that belongs to the P4-ATPase family, specifically functioning as a phospholipid-transporting ATPase. ATP11C plays a critical role in the maintenance of phospholipid asymmetry across the cell membrane by transporting aminophospholipids from the outer leaflet to the inner leaflet of the plasma membrane. This activity is essential for various biological processes, including cell membrane integrity, cell signaling, and apoptosis. ATP11C is particularly important in hematopoiesis, influencing the development of B cells and red blood cells. Mutations or dysregulation in ATP11C can lead to disruptions in cell membrane dynamics and are associated with immunological disorders and anemia. Research on ATP11C continues to focus on its role in phospholipid transport and its implications for cellular function and disease, particularly in the context of blood-related disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP11C
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Atp11c
Gene Accession No. Q9QZW0
Gene Alias A330005H02Rik; AI315324; Atp11c; Atpase 11c, p type; ATPase class VI type 11C; ATPase IQ; ATPase phospholipid transporting 11C; ATPase, class VI, type 11C; ATPIG; ATPIQ; I79_007666; Ig; P4-ATPase flippase complex alpha subunit ATP11C; phospholipid-transporting ATPase 11C; Phospholipid-transporting ATPase IG; probable phospholipid-transporting ATPase 11C; probable phospholipid-transporting ATPase IG; putative phospholipid-transporting ATPase 11C
Gene Symbols Atp11c
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region of Mouse Atp11c.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 320940
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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