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Invitrogen™ ATP11C Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5107072
Description
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% Immunogen sequence: GLKVWVLTGD KMETAKSTCY ACRLFQTNTE LLELTTKTIE ESERKEDRLH.
The ATP11C gene encodes a protein that belongs to the P4-ATPase family, specifically functioning as a phospholipid-transporting ATPase. ATP11C plays a critical role in the maintenance of phospholipid asymmetry across the cell membrane by transporting aminophospholipids from the outer leaflet to the inner leaflet of the plasma membrane. This activity is essential for various biological processes, including cell membrane integrity, cell signaling, and apoptosis. ATP11C is particularly important in hematopoiesis, influencing the development of B cells and red blood cells. Mutations or dysregulation in ATP11C can lead to disruptions in cell membrane dynamics and are associated with immunological disorders and anemia. Research on ATP11C continues to focus on its role in phospholipid transport and its implications for cellular function and disease, particularly in the context of blood-related disorders.
Specifications
ATP11C | |
Polyclonal | |
Unconjugated | |
Atp11c | |
A330005H02Rik; AI315324; Atp11c; Atpase 11c, p type; ATPase class VI type 11C; ATPase IQ; ATPase phospholipid transporting 11C; ATPase, class VI, type 11C; ATPIG; ATPIQ; I79_007666; Ig; P4-ATPase flippase complex alpha subunit ATP11C; phospholipid-transporting ATPase 11C; Phospholipid-transporting ATPase IG; probable phospholipid-transporting ATPase 11C; probable phospholipid-transporting ATPase IG; putative phospholipid-transporting ATPase 11C | |
Rabbit | |
Affinity Chromatography | |
RUO | |
320940 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 | |
Q9QZW0 | |
Atp11c | |
Synthetic peptide corresponding to a region of Mouse Atp11c. | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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