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Invitrogen™ ATP2B1/2/3 Polyclonal Antibody
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Catalog No. PIPA5104020
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PIPA5104020 100 μL
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Catalog No. PIPA5104020 Supplier Invitrogen™ Supplier No. PA5104020
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ATP2B1/2/3.

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP2B1/2/3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ATP2B3
Gene Accession No. Q16720, Q64568
Gene Alias 6430519O13Rik; ATP2B3; ATPase plasma membrane Ca2+ transporting 3; ATPase, Ca++ transporting, plasma membrane 3; CFAP39; cilia and flagella associated protein 39; CLA2; LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3; OPCA; plasma membrane calcium ATPase; Plasma membrane calcium ATPase isoform 3; plasma membrane calcium pump; Plasma membrane calcium pump isoform 3; Plasma membrane calcium-transporting ATPase 3; PMCA3; PMCA3a; SCAX1
Gene Symbols ATP2B3
Host Species Rabbit
Immunogen A synthesized peptide derived from human ATP2B3(Accession Q16720), corresponding to amino acid residues I1005-I1055.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29599, 320707, 492
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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