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Invitrogen™ ATR Monoclonal Antibody (2B5)
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Catalog No. MA123158
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100 μL
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MA123158 100 μL
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Catalog No. MA123158 Supplier Invitrogen™ Supplier No. MA123158
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Raji, Raji nuclear extract. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATR
Applications Functional Assay, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2B5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene ATR
Gene Accession No. Q13535, Q9JKK8
Gene Alias 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
Gene Symbols ATR
Host Species Mouse
Immunogen Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 245000, 545
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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