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Invitrogen™ ATR Polyclonal Antibody
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Catalog No. PIPA120141
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50 μg
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Catalog No. Quantity
PIPA120141 50 μg
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Catalog No. PIPA120141 Supplier Invitrogen™ Supplier No. PA120141
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Whole cell lysate from HeLa and U2OS cells.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATR
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Tris citrate, tris phosphate with 0.1% Sodium azide; pH 7-8
Gene ATR
Gene Accession No. Q13535, Q9JKK8
Gene Alias 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
Gene Symbols ATR
Host Species Rabbit
Immunogen Synthetic peptide representing a portion of the protein encoded within exon 5 (LocusLink ID 545).
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 245000, 545
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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