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Invitrogen™ Atrophin 1 Polyclonal Antibody
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Catalog No. PIPA5101451
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100 μL
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PIPA5101451 100 μL
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Catalog No. PIPA5101451 Supplier Invitrogen™ Supplier No. PA5101451
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Atrophin 1.

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Atrophin 1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ATN1
Gene Accession No. O35126, P54258, P54259
Gene Alias ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD
Gene Symbols ATN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ATN1(Accession P54259), corresponding to amino acid residues T92-E142.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13498, 1822, 29515
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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