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Invitrogen™ Atrophin 1 Polyclonal Antibody
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Catalog No. PIPA556799
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100 μL
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PIPA556799 100 μL
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Catalog No. PIPA556799 Supplier Invitrogen™ Supplier No. PA556799
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HPYAMSPSLG SLRPYPPGPA HLPPPHSQVS YSQAGPNGPP VSSSSNSSSS TSQGSYPCSH PSPSQGPQGA PYPFPPVPTV TTSSATLSTV IATVASSPAG YKTASPPGPP PYGKRAPSPG AYKTATPPGY KPGSPPSFRT GTPPGY Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Atrophin 1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATN1
Gene Accession No. P54259
Gene Alias ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD
Gene Symbols ATN1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Atrophin 1. Recombinant protein control fragment (Product #RP-91651).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1822
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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