Invitrogen™ Atrophin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113590

Catalog No. PIPA5113590

Description

Immunogen sequence: VSTSSSDGKA EKSRQTAKKA RVEEASTPKV NKQGRSEEIS ESESEETNAP For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 100%; Rat: 93%.

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Specifications

• Antigen: Atrophin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATN1
• Gene Alias: ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1822
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P54259
• Gene Symbols: ATN1
• Immunogen: Synthetic peptide directed towards the N terminal region of human ATN1 (aa 38-87).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG