Atropine sulfate monohydrate, 97+%

Description

Atropine sulfate monohydrate, CAS # 5908-99-6, is a muscarinic receptor antagonist. | CAS: 5908-99-6 | H₂SO₄·H₂O | 694.85 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Atropine is a competitive and reversible antagonist of muscarinic acetylcholine receptors on both central and peripheral neurons
• Atropine was originally isolated from the belladonna plant Atropa belladonna but is also found in other Solanaceae plants
• Atropine is a drug that can be used to slow heart rate, decrease salivary secretions, and treat poisoning caused by cholinergic or muscarinic agents

Applications

• It is used to block activation of muscarinic receptors in laboratory mice
• It can be used in a laboratory setting to decrease oral and airway secretions in research animals
• Atropine has been used to study heart rate and blood pressure variability in swine

Specifications

Chemical Identifiers

• CAS: 5908-99-6
• Molecular Formula: H₂SO₄·H₂O
• Molecular Weight (g/mol): 694.85
• MDL Number: MFCD00074815
• InChI Key: PVGPXGKNDGTPTD-IJTOKZDFSA-N
• Synonym: atropine sulfate hydrate, atropine sulfate monohydrate, 1r,3s,5s-8-methyl-8-azabicyclo 3.2.1 octan-3-yl 3-hydroxy-2-phenylpropanoate; methane; sulfuric acid
• PubChem CID: 23624044
• IUPAC Name: [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfuric acid;hydrate
• SMILES: CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O

• Acidity: Passes Test
• Melting Point: >187.0°C
• Color: White
• Ignition Residue: 0.2% max.
• Infrared Spectrum: Authentic
• Assay Percent Range: 97+%
• Packaging: Glass bottle
• Quantity: 100 g
• Beilstein: 21, 27
• Merck Index: 15, 866
• Specific Rotation Condition: −0.60° (25°C per USP)
• Specific Rotation: − 0.60
• Solubility Information: Solubility in water: soluble. Other solubilities: soluble in boiling alcohol and glycerol, slightly soluble in chloroform, practically insoluble in ether
• Formula Weight: 694.85
• Percent Purity: 97+%
• Physical Form: Powder
• Chemical Name or Material: Atropine sulfate monohydrate

Safety and Handling

Hazard Category	GHS Signal Word: Danger
Hazard Statement	GHS H Statement: May cause respiratory irritation. Fatal if swallowed. Causes skin irritation. Fatal if inhaled. May cause an allergic skin reaction. Causes serious eye irritation.
Precautionary Statement	GHS P Statement: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Immediately call a POISON CENTER or doctor/physician. Wear eye protection/face protection. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Avoid breathing dust/fume/gas/mist/vapors/spray. IF ON SKIN: Wash with plenty of soap and water. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

SDS

RUO – Research Use Only