Invitrogen™ Aurora C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 389400

Catalog No. 38-940-0

Description

Aurora C Polyclonal Antibody for Western Blot, ICC/IF

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.

Specifications

• Antigen: Aurora C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AURKC
• Gene Alias: AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20871, 6795
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.25 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: O88445, Q9UQB9
• Gene Symbols: AURKC
• Immunogen: Synthetic peptide derived from an internal region of the human Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora/IPL1/Eg2 protein 2, Aurora/IPL1-related kinase 3) protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG