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Invitrogen™ Aurora C Polyclonal Antibody
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Catalog No. 389400
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100 μg
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Catalog No. Quantity
38-940-0 100 μg
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Catalog No. 38-940-0 Supplier Invitrogen™ Supplier No. 389400
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Description

Rabbit Polyclonal Antibody

Aurora C Polyclonal Antibody for Western Blot, ICC/IF

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
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Specifications

Antigen Aurora C
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene AURKC
Gene Accession No. O88445, Q9UQB9
Gene Alias AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13
Gene Symbols AURKC
Host Species Rabbit
Immunogen Synthetic peptide derived from an internal region of the human Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora/IPL1/Eg2 protein 2, Aurora/IPL1-related kinase 3) protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20871, 6795
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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